Ppt endocrine pharmacology powerpoint presentation. Progesterone has a variety of important functions in the body. Progesterone is a naturally occurring steroid hormone. Pravin prasad ist year resident, md clinical pharmacology maharajgunj medical campus 2nd october, 2015asoj 15, 2072. Pharmacology of female sex hormones linkedin slideshare. Abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as.
Longterm administration of more potent progestins decrease glucose tolerance. Progesterone is a hormone that occurs naturally in the body. New estrogen and progesterone estrogen progesterone. No effect on lipid profile pharmacology of female sex hormones 31 32. Chinese progesterone industry forecasts to 2019 by classification, application and manufacturing technology global and chinese progesterone cas 57830 industry, 20092019 market research report is a professional and indepth market survey on global and chinese progesterone cas 57830 industry.
Chem5398 april 1, 2010 future research how testosterone and estrogen work together to control male dimorphic behaviors in rats ucsf alzheimers disease and estrogen after menopause assigned reading. Male and female hormones pharmacology in rehabilitation f. Progesterone stimulates lipoprotein lipase activity and seems to enhance fat deposition. The primary physiologic effect of progesterone appears to be the induced transformation of uterine endometrial cells so that. The term progestin is sometimes used to refer to the progesterone made in the laboratory that is in oral contraceptives and hormone replacement therapy. New estrogen and progesterone free download as powerpoint presentation.
Bioequivalence and bioavailability forum progesterone. Pregnant women undergo several adaptations in many organ systems. With regard to the progestogenic activity, the timecourse of the serum concentrations of the steroids after the application pharmacokinetics which is dependent upon absorption, metabolism in the gastrointestinal tract and liver firstpass effect, distribution and storage in fat and other tissues, binding to serum proteins, inactivation and conjugation. In addition to progesterone, which can be synthesized and secreted by the ovary, placenta and adrenal glands, there are different classes of progestogens, which also known as. Progestins dr suyash bharat md pharmacology gmc haldwani. In the presence of adequate estrogen, progesterone transforms a proliferative endometrium into a secretory endometrium. Brahma associate professor of pharmacology neigrihms, shillong. Progesterone injection is indicated for the treatment of amenorrhea and abnormal uterine bleeding due to progesterone deficiency. Progesterone pharmacokinetics in healthy women endogenous progesterone is metabolized to 3 biologically active metabolites. Pdf pharmacology of hormone replacement therapy in. Oral contraceptives clinical pharmacy and pharmacology.
Physiologic and pharmacokinetic changes in pregnancy. Dear ashutosh, as progesterone is an highly variable drug that to the intrasubject cv is high the number of subjects for the study will be more nearly 100, due to variable drug you have to go for four way cross over with less no of subjects when compared to two way crossover. The female hormones consist of two principal groups. Onscreen show other titles a free powerpoint ppt presentation displayed as a flash slide show on id. Choose from 500 different sets of sex hormones pharmacology flashcards on quizlet. These changes affect distribution, absorption, metabolism, and excretion of drugs, and thus may impact their pharmacodynamic properties during pregnancy. Progesterone injection is a sterile injectable solution containing the natural female hormone called progesterone. A follicle in the ovary matures, secretes increasing amounts of estrogen, releases an ovum, and is.
Progesterone p4 is an endogenous steroid and progestogen sex hormone involved in the. Other activities to help include hangman, crossword, word scramble, games, matching, quizes, and tests. Progestin is a general term for a substance that causes some or all of the biologic effects of progesterone. Lecture 1 lecture 2 lecture 3 lecture 4 lecture 5 lecture 6 lecture 7 lecture 8 lecture 9 lecture 10 lecture 11.
Learn vocabulary, terms, and more with flashcards, games, and other study tools. Progesterone is a c21steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at c 4c 5. The ovary is the primary source of gonadal hormones in women during the childbearing years ie, between puberty and menopause. It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Discontinue if menstrual flow begins during the injections. We all will try to get the answers for sex hormones. Ppt hormonal drugs powerpoint presentation free to. A powerpoint presentation on estrogens ans antiestrogens suitable for reading by undergraduate level medical students.
Some adaptations are secondary to hormonal changes in. Estrogen and progesterone advanced pharmacology essay. Pharmacology of hormone replacement therapy the pharmacology of hormone replacement therap y is of a particular interest given the complex benefitrisk balance and the importan ce of this. It is also a crucial metabolic intermediate in the production. Progesterone has been established as an obligatory steroid mediator of pregnancy corner, 1947.
Hypothalamus secretes gnrh stimulates pituitary to secrete fsh and lh act on ovary and cause immature ovarian follicles to begin developing to dominant follicles pituitary hormones rising and falling levels create two. Progesterone p4 is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Pravin prasad ist year resident, md clinical pharmacology. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Mechanisms that explain the contraceptive action of. View and download powerpoint presentations on mechanism of hormone action ppt.
Free flashcards to help memorize facts about usmle step 1. Classification and pharmacology of progestins sciencedirect. Mechanisms that explain the contraceptive action of progestin implants for women. The chemical classification of progesterone is progesterone. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. As a hormone, it is involved in the female menstrual cycle, pregnancy and. Start studying pharmacology of estrogen and progesterone dr.
If an internal link led you here, you may wish to change the link to point directly to the intended article. Pharmacology 120 julie cordts instructor pharmacology powerpoint lectures all lessons will open in a new browser window allowing easy access to this menu. Studentshare our website is a unique platform where students can share their papers in a matter of giving an example of the work to be done. The progesterone it is the steroid sex harmone secreted by the corpus luteum, adrenal glands and placenta. Ppt hormonal drugs powerpoint presentation free to download id. Find powerpoint presentations and slides using the power of, find free presentations research about mechanism of hormone action ppt. Prometrium progesterone, usp capsules contain micronized progesterone for oral administration. Clinical pharmacology progesterone is a naturally occurring steroid that is secreted by the ovary, placenta, and adrenal gland. Pharmacology of sex hormones progesterone, estrogens, testosterones prof.
When properly regulated by folliclestimulating hormone fsh and luteinizing hormone lh from the pituitary, each menstrual cycle consists of the following events. All women who start taking oral contraceptives should first have a pregnancy test to make sure they are not already pregnant. Oral contraceptives can be started any day of the week and any day of the menstrual cycle. Estrogens and progestins are endogenous hormones that produce numerous physiological actions. Progesterone is an endogenous steroid and progestogen sex hormone. Hormones are vital for maintaining normal health, growth, development and various other aspects of the body. Oral contraceptives presentation free download as powerpoint presentation. Pharmacology in nursing women s health drugs bc the have a pharmacology in nursing women s health drugs bc the have a chemical structure like a. Administration of estrogen and progesterone by means of oral, transdermal or depot injection methods inhibits ovulation by the process of negative feedback inhibition. Progesterone produced by the corpus luteum during the luteal phase is necessary to promote secretory transformation of endometrial tissue in preparation for embryo implantation. If estrogen is also given, start progesterone 2 weeks after starting estrogen. Pharmacological actions of estrogen, progesterone and drugs actions on uterus.
Progesterone is essential for the development of decidual tissue, and the effect of progesterone on. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Schindler ae1, campagnoli c, druckmann r, huber j, pasqualini jr, schweppe kw, thijssen jh. Progesterone pharmacokinetics and pharmacodynamics with 3. Potent, subtypeselective estrogen receptor agonist ec 50 200 pm. Physiologic changes in pregnancy induce profound alterations to the pharmacokinetic properties of many medications. It is the major progestogen and is required for the production of other endogenous steroids. Women should also use backup birth control, such as condoms, for 7 days after starting. Using progestins in clinical practice american family. Goodman and gilmans pharmacological basis of therapeutics pp. Learn sex hormones pharmacology with free interactive flashcards. This disambiguation page lists articles associated with the title pharmacology of progesterone.
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